GENOME

GENOME is an amp modeler, effects suite, and virtual cabinet engine for guitar and bass. Its CODEX engine loads Neural Amp Modeler, AIDA-X, and Proteus captures, and the product page says the software includes more than 40 premium AI amp captures. Users can build series or parallel signal paths, with up to 12 components per lane and dual-lane expansion. GENOME runs as a standalone app or as a VST3, AU, or AAX plugin; the maker lists Pro Tools, Logic Pro X, Ableton Live, Cubase, Studio One, and Reaper as tested DAWs. It also supports parameter automation, MIDI mapping, and MIDI Learn for external hardware control. The free GENOME Intro plan includes four TSM-Ai amplifiers, 14 pedals, five DynIR cabinets, and four Studio FX. The GENOME license costs $89.99, paid once and includes 24 amps, 49 pedals, 16 DynIR cabinets, and 16 Studio FX, excluding FairTone and Artist Series premium components. A Two notes account is required, and desktop licensing does not include GENOME iOS.

GENOME combines amp capture loading, effects, cabinet modeling, and flexible routing for guitar and bass workflows. Check the license contents and separate iOS access requirement before choosing a plan.

GENOME suits guitarists and bassists looking to use amp captures, effects, and virtual cabinets in a standalone app or DAW. Its MIDI tools also suit users controlling parameters with external hardware.

GENOME is an amp-modeling and effects environment for guitar and bass, designed for players who want to work with amp captures as well as modeled cabinets and effects. It suits musicians building software signal chains for standalone use or a DAW, though iPad users need a separate access pass.

Overview

GENOME combines amp, effects, and virtual-cabinet processing in one application. Its CODEX engine loads Neural Amp Modeler, AIDA-X, and Proteus captures in the same workflow, and the product includes more than 40 premium AI amp captures. That breadth makes it a flexible option for players bringing different capture formats together rather than committing to one.

Series and parallel routing, up to 12 components per lane, and dual-lane expansion allow more involved signal paths than a simple linear chain. GENOME runs standalone or as a plugin, but requires a Two notes account. The account requirement is a practical condition for use, not just an optional route to extra features.

Key features

Amps, cabinets, and effects

The paid GENOME plan includes 24 amps, 49 pedals, 16 DynIR cabinets, and 16 Studio FX. The product also describes 65 effects overall and includes an IR loader. This is a substantial core toolkit, but it is not the full premium catalog: FairTone and Artist Series components are excluded, so buyers should not assume the license covers every premium component associated with GENOME.

Routing and control

Parameter automation, MIDI mapping, and MIDI Learn support control from external MIDI hardware and automation in a project. Those options matter most to players who want to change settings as part of a performance or DAW arrangement; they add less for someone seeking only a basic fixed amp-and-cab setup. Two notes lists Captor, Captor X, OPUS, and ReVolt hardware as compatible.

DAW and plugin support

GENOME is available as a standalone app and in VST3, AU, and AAX formats. The maker lists Pro Tools, Logic Pro X, Ableton Live, Cubase, Studio One, and Reaper as tested DAWs. That range gives desktop users several ways to fit it into an existing recording setup.

Pricing

Intro is a useful no-cost way to work with a smaller selection of amps, pedals, cabinets, and studio effects. Its compact collection makes it less suitable for players who need the paid plan's wider component range. GENOME costs $89.99, paid once and is the better fit for buyers who want that larger catalog without a recurring plan. A 14-day free trial license lets users test GENOME and its components before choosing; the paid plan still excludes FairTone and Artist Series premium components.

Platforms

The download page offers GENOME 2.1 for macOS 10.15 or newer, Windows 64-bit, and iPad with iOS 12 or newer. A desktop license does not include GENOME iOS: iPad users need an iOS Access Pass separately. This distinction matters for anyone expecting one desktop purchase to cover both desktop and tablet use.

Who it's for

GENOME is best suited to guitarists and bassists who want compatible captures, amp and cabinet processing, and flexible routing in one standalone tool or DAW plugin. Its MIDI controls and component capacity will appeal to players building more elaborate chains. It is a weaker fit for someone who needs a broad free collection, wants iOS access bundled with a desktop license, or expects FairTone and Artist Series components in the main paid plan.

Pros and cons

• Pros: Loads NAM, AIDA-X, and Proteus captures in one workflow, giving users flexibility across three capture formats.
• Pros: Series and parallel routing, dual-lane expansion, and up to 12 components per lane support complex chains.
• Pros: Standalone, VST3, AU, and AAX formats cover several desktop workflows.
• Cons: Intro has only 4 amplifiers, 14 pedals, 5 cabinets, and 4 Studio FX, limiting its reach for players who need variety.
• Cons: The paid license excludes FairTone and Artist Series components, leaving some premium content outside the core purchase.
• Cons: Desktop licensing does not include iOS access, which requires an additional Access Pass.
• Cons: A Two notes account is required to use the software.

Alternatives

For a wider comparison of guitar-focused tools, browse Guitar Amp Software. TH-U is worth considering if its paid plans and free trial suit your needs; it spans iOS, macOS, and Windows. Amp ONE is a free iOS option if you want a no-cost alternative limited to that platform. IK Multimedia ReSing is another freemium choice for macOS and Windows, with a free tier and a one-time paid plan.

Amp Locker may suit users who prefer a free download and buying extra modules individually, and it supports Linux as well as macOS and Windows. Amped offers a free plan and trial for macOS and Windows. Amplifikation 360 is a freemium macOS and Windows alternative. Helix Stadium Native also has a free plan and trial for macOS and Windows. Guitarix is a free option for Linux and macOS.

Verdict

Choose GENOME if you want broad capture-format support, a sizeable amp-and-effects collection, and room to build routed guitar or bass chains in a standalone app or DAW. Its clearest drawbacks are the narrow Intro tier, exclusions from the paid component catalog, and separate iOS access. Players who need a more generous free collection or a desktop license that covers iPad should look elsewhere.