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Case It!
What it is
Case It! is a free framework for collaborative, case-based learning in molecular biology. Version 705 simulates laboratory procedures using DNA or protein sequences, including PCR, qPCR, gel electrophoresis, restriction enzyme digestion, ELISA, microarrays, and Southern and Western blots. It supports plasmid DNA, 5′-labelled gels, and searching and viewing restriction enzyme sites, including Cas9 sites, in double-stranded DNA. Connections with bioinformatics software and websites support sequence alignment and tree-building; the project also notes sequence searches as useful for undergraduate research. The download includes DNA and protein sequences referenced in case descriptions, covering subjects such as genetic and infectious diseases. Case It Mobile provides selected cases on phones and tablets through scenarios and videos of simulated procedures. Cases not converted for mobile and custom-sequence work require v705. The project says v705 runs on current Windows and Mac systems and documents an M-series Mac setup using UTM and Windows 11 Pro. Students, instructors, and IT professionals can download it free for educational use after submitting a form.
For and against
For
- Free for educational use
- Simulates a broad set of molecular biology procedures
- Includes sequence alignment and tree-building connections
- Selected cases are available through Case It Mobile
Against
- Custom sequences require downloading v705
- Mobile access covers only selected converted cases
The verdict
Case It! combines case-based learning with molecular biology procedure simulations and sequence tools. Mobile access is limited to selected cases; v705 is needed for custom sequences and other cases.
Who it suits
Case It! suits students and instructors using molecular biology cases and simulated lab procedures for education, as well as IT professionals obtaining the educational download.
Plans and prices
Case It v705 educational use
Free of charge for educational use
Read 2 Oct 2026 · caseitproject.org
On the record
- Bioinformatics
- Case It integrates with bioinformatics software and websites for sequence alignment and tree-building.caseitproject.org · read 2 Oct 2026
- CRISPR features
- The software supports plasmid DNA, 5′-labelled gels, and searching and viewing restriction enzyme sites, including Cas9 sites, in double-stranded DNA.caseitproject.org · read 2 Oct 2026
- Download access
- Students, instructors, and IT professionals can download the software free for educational use after submitting a form; the page says names and email addresses are kept confidential.caseitproject.org · read 2 Oct 2026
- Included cases
- The download includes DNA and protein sequences referenced by case descriptions, covering subjects such as genetic and infectious diseases.caseitproject.org · read 2 Oct 2026
- Lab procedures
- Listed procedures include qPCR, SNP and expression microarrays, restriction enzyme digestion, gel electrophoresis, PCR, ELISA, Southern and Western blots, and dot blots.caseitproject.org · read 2 Oct 2026
- Maker credits
- The credits page names Mark Bergland, Karen Klyczek, and Chi-Cheng Lin for software and says Case It Software is authored with Director MX.caseitproject.org · read 2 Oct 2026
- Mobile access
- Case It Mobile offers selected cases on smartphones and tablets through case scenarios and videos of simulated procedures, without downloading v705.caseitproject.org · read 2 Oct 2026
- Mobile limitation
- Cases not converted to mobile format and use of custom sequences require downloading Case It v705.caseitproject.org · read 2 Oct 2026
- Operating systems
- The project says v705 runs on current Windows and Mac operating systems and documents an M-series Mac setup using UTM and Windows 11 Pro.caseitproject.org · read 2 Oct 2026
- Purpose
- Case It provides a framework for collaborative case-based learning in molecular biology.caseitproject.org · read 2 Oct 2026
- Sequence search
- The project lists sequence search capabilities as useful for undergraduate research applications.caseitproject.org · read 2 Oct 2026
- Simulation
- Case It v705 performs common laboratory procedures on DNA or protein sequences.caseitproject.org · read 2 Oct 2026
